Fuente: PubMed "meat" J Chromatogr A. 2026 Mar 24;1775:466934. doi: 10.1016/j.chroma.2026.466934. Online ahead of print.ABSTRACTBased on the concept of efficient and rapid detection, a carbon nanotube-based magnetic molecularly imprinted polymer was developed in this study. A series of characterization techniques were employed to investigate the structure and morphology of the material. The adsorption performance was investigated using static and dynamic adsorption experiments as well as selectivity tests, demonstrating that the imprinted layer was uniform and structurally stable. Adsorption experiments indicated that the material had significant advantages in binding capacity and selective recognition, effectively distinguishing florfenicol and its structural analogs. By combining magnetic solid-phase extraction with high-performance liquid chromatography-tandem mass spectrometry, an efficient detection method for florfenicol in fish meat samples was established. Methodological validation demonstrated a limit of detection of 1.65 ng/kg, a limit of quantification of 5.00 ng/kg, recovery rates of 90.3 %-111 %, standard deviations of 0.470 %-6.20 %, and relative standard deviations of 0.490 %-6.25 %. The results indicated that the prepared magnetic molecularly imprinted polymers not only achieved efficient detection of florfenicol but also provided a feasible new approach for monitoring veterinary drug residues in aquaculture, which is important for safeguarding food safety and public health.PMID:41905307 | DOI:10.1016/j.chroma.2026.466934