Fecha de publicación: 15/01/2025 Fuente: Biomolecules - Revista científica (MDPI) Biomolecules, Vol. 15, Pages 134: Multi-Omics Insights into Regulatory Mechanisms Underlying Differential Deposition of Intramuscular and Abdominal Fat in Chickens
Biomolecules doi: 10.3390/biom15010134
Authors:
Yuxin Xing
Chenglin Ma
Hongbo Guan
Jianing Shen
Ying Shen
Guoxi Li
Guirong Sun
Yadong Tian
Xiangtao Kang
Xiaojun Liu
Hong Li
Weihua Tian

Excessive abdominal fat deposition in chickens disadvantages feed conversion, meat production, and reproductive performance. Intramuscular fat contributes to meat texture, tenderness, and flavor, serving as a vital indicator of overall meat quality. Therefore, a comprehensive analysis of the regulatory mechanisms governing differential deposition of abdominal versus intramuscular fat is essential in breeding higher-quality chickens with ideal fat distribution. This review systematically summarizes the regulatory mechanisms underlying intramuscular and abdominal fat traits at chromatin, genomic, transcriptional, post-transcriptional, translational, and epigenetic-modification scales. Additionally, we summarize the role of non-coding RNAs and protein-coding genes in governing intramuscular and abdominal fat deposition. These insights provide a valuable theoretical foundation for the genetic engineering of high-quality and high-yielding chicken breeds.