CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL

Fecha de publicación: 05/01/2023
Fuente: Wipo Milk or dairy products
Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.