Glycerin suppositories as inexpensive multi-sequence MRI skin markers

Fecha de publicación: --
Fuente: PubMed "olive oil"
Skeletal Radiol. 2026 Nov 9. doi: 10.1007/s00256-026-05430-w. Online ahead of print.ABSTRACTOBJECTIVE: To assess MRI conspicuity and clinical usability of a commercially available glycerin suppository as a low-cost skin marker for musculoskeletal MRI across routine sequences.MATERIALS AND METHODS: A glycerin suppository was compared in vivo with vitamin E, water, olive oil, and diluted gadoteric acid solution across routine musculoskeletal MRI sequences. Conspicuity was scored independently by two musculoskeletal radiologists on a 4-point ordinal scale. Clinical usability was retrospectively assessed in 130 examinations at 1.5 and 3 T. One fat-sensitive image set (conventional T1-weighted or Dixon fat-only) and one fluid-sensitive set were scored independently by two readers. Scores of 2 or higher defined usability. Inter-reader agreement was assessed with Cohen kappa.RESULTS: Experimentally, the glycerin suppository showed the most consistent multi-sequence visibility among the tested markers. Unlike vitamin E markers, it remained highly conspicuous on fat-suppressed T1-weighted, fat-suppressed T2-weighted, and Dixon water-only images; it remained visible on STIR but showed lower conspicuity on Dixon fat-only images. Packaging did not affect visibility. Clinically, the marker was usable on both image sets in 123/130 examinations (94.6%) for reader 1 and 120/130 (92.3%) for reader 2. Usability on conventional T1-weighted images was 100% for both readers but decreased on Dixon fat-only reconstructions to 80.0% and 66.7%, respectively. Weighted kappa was 0.90 for fat-sensitive and 0.88 for fluid-sensitive scores. No marker-related image-quality degradation occurred.CONCLUSION: Glycerin suppositories are inexpensive, disposable MRI skin markers with broad sequence visibility. Their limitation is reduced conspicuity on Dixon fat-only reconstructions.PMID:43002240 | DOI:10.1007/s00256-026-05430-w