Fecha de publicación: 25/03/2022 Fuente: Wipo "olive oil" The invention provides a ceramide-containing grease composition, the grease is selected from vegetable grease, animal grease or a combination thereof, the vegetable grease is selected from shea butter, olive oil, safflower seed oil, meadowfoam seed oil, plant squalane or a combination thereof, the animal grease is deep sea fish oil, and the ceramide-containing grease composition is prepared from ceramide. Based on the total weight of the composition, the composition comprises 0.01 to 5 weight percent of ceramide. The invention also relates to an application of the grease composition containing ceramide in enhancing the skin barrier function and/or in preparing a medicine for enhancing the skin barrier function and/or an external preparation for the skin.