Fuente: WIPO "olive oil" The present invention refers to an olive oil-in-water microemulsions comprising mycobacterium species which exhibiting high stability and homogeneity and which have also a therapeutic effect in the treatment of bladder cancer. The microemulsions disclose in the present invention remain stable and ensures also the mycobacteria viability. Moreover the present invention discloses the pharmaceutical compositions comprising the olive oil-in-water microemulsion and the therapeutic uses thereof.