Fuente: WIPO "olive oil" Compositions, methods of making, and uses are provided that relate to a continuous medium forming a first phase and a discrete phase particle containing a second phase. The discrete phase particle includes one or more compounds derived from Olea europaea, such as oleocanthal, oleacein, certain amounts of oleocanthal and oleacein, and polyphenols. Such compositions can be used to administer an active ingredient to a subject, including topical and oral administration routes. The discrete phase compound including the one or more compounds derived from Olea europaea can exhibit certain antioxidant and/or anti-inflammatory effects in maximizing delivery and uptake of the composition, where such effects can protect the active ingredient contained therein as well as provide advantageous secondary or compound effects in addition to those provided by the active ingredient.