Fuente: "milk OR dairy products" Sci China Life Sci. 2026 Apr 29. doi: 10.1007/s11427-025-3224-6. Online ahead of print.ABSTRACTTraditional selective breeding relies on observable phenotypic traits. Recent advances in omics technologies (e.g., genomics, transcriptomics, proteomics, and metabolomics) have revolutionized phenotyping in animal genetic breeding by providing deeper insights into complex traits and improving the efficiency of breeding programs. This review summarizes the applications of omics-based phenotyping technologies to improve the phenotypic traits, such as meat, egg, milk and wool quality, as well as yield, disease resistance and stress tolerance. Integrative multi-omics data enable the identification of key candidate genes, biomarkers and regulatory networks, thereby allowing earlier and more precise selection in breeding programs. The adoption of omics-driven strategies is accelerating the genetic enhancement of the economically important traits, offering a comprehensive framework to improve animal productivity and health. Nevertheless, significant challenges remain, including constructing species and traits-specific omics databases, establishing robust correlations between omics-derived phenotypes and traditional traits, and translating omics discoveries into practical breeding solutions.PMID:42113448 | DOI:10.1007/s11427-025-3224-6