Fuente: WIPO "dairy products" A composition of lactoferrin, osteopontin and calcium in defined proportions, which can alleviate and inhibit the expression of pro-inflammatory factors at the mRNA level in RAW264.7 macrophages induced by LPS, and down-regulate the expression of inflammatory pathway-associated proteins at the protein level, thereby alleviating the effects of inflammatory responses. Use of the composition in the preparation of a product for resisting enteritis and/or protecting the integrity of the intestinal barrier.