Transgenic mice producing bovine .alpha.-lactalbumin in their milk

Fuente: WIPO "milk"
The present invention relates to the use of a mammary specific .alpha.-lactalbumin regulatory sequence to assist in the production of recombinant proteins in mammals' milk. The invention also relates to the genetically engineered mammal that produces the desired recombinant product in its milk and to the products produced by the genetically engineered mammal, including the altered composition of milk and the semen which includes the desired .alpha.-lactalbumin protein DNA sequence.