Fecha de publicación: -- Fuente: PubMed "wine" Food Funct. 2026 Nov 6. doi: 10.1039/d6fo02375d. Online ahead of print.ABSTRACTThe influence of (poly)phenols from red wine on muscle health in older adults remains unclear. This study aimed to investigate associations between urinary biomarkers of wine (poly)phenol intake and sarcopenia-related parameters in older adults. Fifty participants, classified as probable sarcopenic (n = 29) or non-sarcopenic (n = 21), with a mean age of 69.1 ± 4.3 years, underwent assessment of muscle strength, bioimpedance, muscle ultrasound, isokinetic performance, and urinary (poly)phenol biomarkers quantified by high-performance liquid chromatography. Urinary biomarkers, including catechin sulfate, methyl-catechin sulfate, and resveratrol derivatives, showed positive associations with handgrip strength, skeletal muscle mass, appendicular skeletal muscle mass and indices. Positive associations were also observed with ultrasound-derived quadriceps and rectus femoris muscle thickness and rectus femoris cross-sectional area, predominantly in women. These findings support associations between wine-derived (poly)phenol metabolites and muscle health. Prospective studies and intervention trials, ideally using dealcoholized wine to isolate the effects of (poly)phenols from those of ethanol, are warranted.PMID:42992506 | DOI:10.1039/d6fo02375d