Glaucoma Management in Sturge-Weber Syndrome Using the Delphi Process

Fuente: PubMed "wine"
Ophthalmol Glaucoma. 2025 Nov 26:S2589-4196(25)00242-X. doi: 10.1016/j.ogla.2025.11.003. Online ahead of print.ABSTRACTOBJECTIVE: We sought to identify areas of consensus and non-consensus in the ophthalmic screening, diagnosis and management of SWS.DESIGN: Modified Delphi methodology.PARTICIPANTS: North American glaucoma experts with prior experience managing glaucoma in patients with Sturge-Weber syndrome.METHODS: A modified Delphi process was used as a systematic and structured communication technique, consisting of two rounds of electronic questionnaires to a wider group followed by an in-person meeting of selected experts. Questions that did not reach agreement were reformulated in each round, with the aim to reach consensus. Our study did not require IRB review or adjudication based on their policies as reflected in the supporting document. Our submission adhered to the Declaration of Helsinki.MAIN OUTCOME MEASURES: Consensus was defined as agreement among at least 85% of participants for the electronic questionnaires or a minimum of 70% during the in-person meeting.RESULTS: Amongst other recommendations, the panel concluded that all patients with a facial port-wine birthmark should be assessed for glaucoma within a month of birth, with shorter screening intervals thereafter in patients with bilateral eyelid involvement, choroidal hemangioma and signs of elevated episcleral venous pressure. There was no consensus on timing of follow up visits. In children ≥4 years with signs of glaucoma, medical intervention is the initial consideration. In children <4 years, the primary intervention is likely to be surgical, with some form of goniosurgery as the first-choice procedure.CONCLUSIONS: Consensus for screening, diagnosis and management in patients with SWS is designed to hopefully improve clinical practice and patient outcomes. Questions where consensus was not reached may highlight variations in practice, conflicting evidence or areas that might benefit from further research and investigation.PMID:41314339 | DOI:10.1016/j.ogla.2025.11.003