The invention relates to a wine brewing energy comprehensive system based on heat pump heat supply. The wine brewing energy comprehensive system comprises a heat pump heat supply system, a flash evaporation steam supply system, a flash evaporation heat supply system, a fresh air supply system, a drying air supply system and a heat supply air supply system. Various waste heat resources existing in the wine brewing process are fully recycled and utilized through the combination of the waste heat recovery device and the waste heat utilization device, the overall energy utilization efficiency in the wine brewing process is effectively improved, and the water consumption for wine brewing is reduced.