Fecha de publicación: -- Fuente: WIPO "tomato" The current disclosure relates to a soluble antibody or antibody fragment, wherein the antibody or antibody fragment is a modulator of Wnt7 signaling pathway, preferably an agonist of the Wnt7 pathway, and wherein said antibody or antibody fragment comprises one or more LRP binding domains, one or more Gpr124 binding domains, and one or more Reck binding domains. The disclosure also relates to uses of said antibody or antibody fragment.