T Cell Engager Masking Molecules

Fecha de publicación: --
Fuente: WIPO "tomato"
The present invention relates to T cell engager masking molecules, and methods related thereto, that reduce the severity of cytokine release syndrome, wherein said molecules have (i.) a binding peptide which binds to a T-cell engaging paratope of a bispecific T cell engager molecule (TCE), (ii.) a linker, and (iii.) a half-life extending polymer.