SACCHARIDE IMPORTERS FOR LACTO-N-TRIOSE

Fuente: WIPO "tomato"
This disclosure is in the technical field of synthetic biology, metabolic engineering and cell cultivation. This disclosure provides a cell for the production of one or more bioproduct(s) wherein the cell is capable to produce one or more precursor(s) used in the production of the one or more bioproduct(s) and wherein the cell is genetically engineered to express a saccharide importer that internalizes at least one of the one or more precursor(s). This disclosure furthermore provides a cell that is genetically engineered to express or to overexpress a saccharide importer that has uptake activity for lacto-N-triose (LN3, GlcNAc-beta1,3-Gal-beta1,4-Glc). The invention also provides the use of the cells in a cultivation or incubation. The invention also describes methods for the production of one or more bioproduct(s) using any one of the saccharide importers as well as the purification of the bioproduct(s). The invention furthermore relates to saccharide importers having uptake activity for LN3 and the use of any one of the saccharide importers for the production of one or more bioproduct(s).