PSYCHROPHILIC AND THERMOLABILE CRISPR RIBONUCLEOPROTEIN COMPLEX AND THE USE THEREOF

Fuente: WIPO "tomato"
The invention relates to a ribonucleoprotein complex comprising: a nuclease characterized as CRISPR-associated protein having a sequence identity of at least 90% to sequence SEQ ID NO: 1, and a dual or single guide RNA. Likewise, the present invention also relates to the use of said ribonucleoprotein to bind, modify or alter target sequences in the genome of a cell or organism, or to modify the gene expression of a cell.