NOVEL ANTHELMINTIC CRY PROTEINS AND USES THEREOF

Fuente: WIPO "tomato"
Compositions and methods for treating or reducing the severity or likelihood of occurrence of a parasitic worm infection in a human, an animal, or a plant are described. Compositions including isolated, native, bioactive crystals of CryH1 or CryH13 and inactivated or live recombinant bacteria expressing a CryH1 or CryH13 crystal proteins in the cytosol of the bacterium are described. Compositions suitable for pharmaceutical and agricultural applications are provided. Methods of administering a therapeutically effective amount of a composition to a human or animal suffering from a parasitic worm infection are provided. Compositions are provided for use as animal feed, feed supplement, or in waste treatment. Methods of agricultural applications for control of parasitic worm infections are provided.