Fuente: WIPO "tomato" A system for optimizing supplement decisions is disclosed. The system includes a computing device configured to receive a longevity inquiry from a remote device. The system retrieves a biological extraction pertaining to a user and identifies a longevity element associated with a user. The system selects an ADME model utilizing a biological extraction. The system generates a machine-learning algorithm utilizing the selected ADME model to input a longevity element associated with a user as an input and output an ADME factor. The system identifies a second longevity element compatible with the ADME factor as a function of the first longevity element. The system selects the second longevity element as a tolerant longevity element. A method for optimizing supplement decisions is also disclosed.