Fecha de publicación:
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Fuente:
WIPO "tomato"
The invention is situated in the field of cell culturing and disease modeling. More specifically, the invention relates to a method for obtaining a neuromuscular 3D organoid demonstrating myelination that is derived from stem cells. The invention further relates to a neuromuscular organoid obtained using the method of the invention which can be used to study (peripheral) neuropathic diseases, in particular Charcot-Marie-Tooth disease characterized by myelination and/or axonal defects.