Fecha de publicación: 26/12/2024 Fuente: WIPO "tomato" This disclosure provides a novel magnetic nanoparticle-assisted genome editing (MAGE) platform, which significantly improves transfection efficiency and biocompatibility in stem cells as well as the efficiency of CRISPR-Cas systems. Due to the great potential of CRISPR-Cas systems, the disclosed MAGE platform can be used for a host of applications in stem cell therapy for genetic disorders.