Fecha de publicación: 26/12/2024 Fuente: WIPO "tomato" There is provided a lipid nanoparticle comprising (a) from about 40 to 100 mol % of an ionizable lipid; (b) from 0 to about 10 mol % of a neutral lipid; (c) from 0 to about 50 mol % of a helper lipid; (d) from 0 to about 5 mol % of a polymer-conjugated lipid; and (e) from 0 to about 5 mol % of a hydrophobic component; wherein the ionizable lipid is at least one compound of formula (I): or a pharmaceutically acceptable salt thereof. The lipid nanoparticle can comprise a cargo and can be used for delivering a cargo to a cell.