Fuente: WIPO "tomato" The present disclosure relates to methods and compositions of genetically engineered microbes, for improved control of pathogens, such as bacteria and/or fungi, with application in various fields, such as pharmaceuticals and agriculture. The genetically engineered microbes may comprise a deletion or knockout at one or more genomic loci, that confers capability of reducing hyphal growth of a fungus, reduce spore formation of a fungus, and/or other benefits.