Fecha de publicación: -- Fuente: WIPO "tomato" Described herein are polypeptides and methods of use of such polypeptides. Also described herein are complexes, compositions, and systems including polypeptides of the present invention, each of which may be used for modifying and/or editing a target nucleic acid. A polypeptide of the present invention may be an enzyme that generates DNA (e.g., cDNA) from RNA.