Fecha de publicación: 09/01/2025 Fuente: WIPO "tomato" The present invention relates to a GB1 domain fusion structure for upregulating recombinant protein expression in plants and, more specifically, to a GB1 domain fusion structure in which the GB1 domain of Streptococcus-derived protein G is fused with a target protein to be expressed in an upregulated manner, and a method for upregulating expression of a recombinant protein by using same. The present invention can bring about a reduced risk of contamination by pathogens and a high production yield, compared to the case of employing animal cells or microbes conventionally established to produce recombinant proteins, and a remarkable improvement in recombinant protein output, compared to the conventional case of employing plants. Thus, the present invention has several advantages in terms of quality and economy and thus can be a very competitive production method in the commercial production of recombinant proteins.