Fuente: WIPO "tomato" Described herein are a composition or a construct including a first polypeptide and a second polypeptide. The first polypeptide includes a growth arrest-specific 6 (GAS6) polypeptide or a protein S polypeptide, and the second polypeptide includes an annexin V polypeptide. Also described is a method of treating, ameliorating and/or preventing a disease or disorder caused by or involves a vascular occlusion or damage.