Fuente: WIPO "tomato" Described herein are compositions including at least one of lotus leaf extract (LLE), Chrysanthemum morifolium extract (CME), and Pu'er tea extract (PTE) having an agonistic effect on glucagon-like peptide-1 receptor (GLP-1R). Also, described herein are compositions including a mixture of LLE, CME and PTE having a greater effect on pancreatic lipase inhibition as compared to the individual extracts. Methods of using the described compositions, e.g., for supporting weight loss efforts in a subject in need of thereof are also described.