Fuente: WIPO "tomato" Abstract of the Disclosure: A method of manufacturing a composition for inducing defense in a plant includes infecting a plant with a virus to produce a virus-like nanoparticle, sampling symptomatic leaves from the plant, homogenizing the virus-like nanoparticle, incubating the virus-like nanoparticle, centrifuging the virus-like nanoparticle, and filtrating the virus-like nanoparticle.