Fuente: WIPO "tomato" Provided are Bifidobacterium breve and a probiotic composition comprising the strain. Bifidobacterium breve was deposited in the Bioresource Collection and Research Center of Food Industry Research and Development Institute Taiwan, China on August 8, 2022, and the deposit number BCRC 911145 was obtained. Further provided is use of the strain or a culture thereof in the preparation of a composition for inhibiting maturation of adipocytes, a composition for reducing fat accumulation and/or promoting fat metabolism, a composition for reducing weight, a composition for regulating blood esters, or a composition for regulating blood glucose.