Fecha de publicación: -- Fuente: WIPO "tomato" Synthetic Tombusviridae satellite RNA molecules and satellite particles containing the same are disclosed. Synthetic Tombusviridae satellite RNA molecules which contain internal heterologous RNA virus (HRV) amplicons are also disclosed. Also disclosed are methods of using the Tombusviridae satellite RNA molecules and satellite particles containing the same to change plant phenotypes, improve plant stress resistance, and improve plant pest and pathogen resistance.