The Science of Cannabis Trichomes

Trichomes are the cannabinoid factories of the cannabis plant. But what do we actually know about them? Read More (Feed generated with FetchRSS)

Fuente: Analytical Cannabis Articles

A Multicriteria Decision Analysis Comparing Pharmacotherapy for Chronic Neuropathic Pain, Including Cannabinoids and Cannabis-Based Medical Products

Cannabis Cannabinoid Res. 2021 Mar 17. doi: 10.1089/can.2020.0129. Online ahead of print.ABSTRACTBackground: Pharmacological management of chronic neuropathic pain (CNP) still represents [...]

Fuente: PubMed "Cannabis"

A Unique Case of Bulimia-Induced Purging Immediately Followed by Cannabis-Induced Hyperemesis: Is There a Co-Relation?

Prim Care Companion CNS Disord. 2021 Mar 25;23(2):20l02769. doi: 10.4088/PCC.20l02769.NO ABSTRACTPMID:34000152 | DOI:10.4088/PCC.20l02769

Fuente: PubMed "Cannabis"

Authorization Patterns, Safety, and Effectiveness of Medical Cannabis in Quebec

Cannabis Cannabinoid Res. 2021 May 10. doi: 10.1089/can.2020.0140. Online ahead of print.ABSTRACTIntroduction: Despite increasing demand for data, little is known about the authorization [...]

Fuente: PubMed "Cannabis"

Call for Special Issue Papers: Cannabidiol

Cannabis Cannabinoid Res. 2021 May 7. doi: 10.1089/can.2021.29016.cfp. Online ahead of print.NO ABSTRACTPMID:33998901 | DOI:10.1089/can.2021.29016.cfp

Fuente: PubMed "Cannabis"

Cannabidiol-Driven Alterations to Inflammatory Protein Landscape of Lipopolysaccharide-Activated Macrophages In Vitro May be Mediated by Autophagy and Oxidative Stress

Cannabis Cannabinoid Res. 2021 Mar 25. doi: 10.1089/can.2020.0109. Online ahead of print.ABSTRACTBackground: The nonpsychotropic phytocannabinoid cannabidiol (CBD) presents itself as [...]

Fuente: PubMed "Cannabis"

Cannabinoid Content in Cannabis Flowers and Homemade Cannabis-Based Products Used for Therapeutic Purposes in Argentina

Cannabis Cannabinoid Res. 2021 Mar 26. doi: 10.1089/can.2020.0117. Online ahead of print.ABSTRACTIntroduction: A recent law (DCTO-2020-883-APN-PTE-Law No. 27,350. Regulation) passed [...]

Fuente: PubMed "Cannabis"

Cannabinoid Profiles in Medical Cannabis Users: Effects of Age, Gender, Symptoms, and Duration of Use

Cannabis Cannabinoid Res. 2021 May 17. doi: 10.1089/can.2020.0120. Online ahead of print.ABSTRACTIntroduction: Clinical trials remain the gold standard for evaluating efficacy, but there [...]

Fuente: PubMed "Cannabis"

Cannabinoid Receptor Subtype-1 Regulates Allergic Airway Eosinophilia During Lung Helminth Infection

Cannabis Cannabinoid Res. 2021 Apr 8. doi: 10.1089/can.2020.0167. Online ahead of print.ABSTRACTIntroduction: Over 1 billion humans carry infectious helminth parasites that can lead [...]

Fuente: PubMed "Cannabis"

Clinician Beliefs and Practices Related to Cannabis

Cannabis Cannabinoid Res. 2021 Apr 26. doi: 10.1089/can.2020.0165. Online ahead of print.ABSTRACTIntroduction: Medical cannabis (marijuana) use is legal in 33 U.S. states and the District [...]

Fuente: PubMed "Cannabis"

Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor

Cannabis Cannabinoid Res. 2021 Apr 16. doi: 10.1089/can.2020.0107. Online ahead of print.ABSTRACTBackground: The endocannabinoid system is present in multiple organ systems and is involved [...]

Fuente: PubMed "Cannabis"

Evolving Global Perspectives of Pharmacists: Dispensing Medical Cannabis

Cannabis Cannabinoid Res. 2021 Apr 16. doi: 10.1089/can.2020.0144. Online ahead of print.ABSTRACTIntroduction: Different countries have employed a variety of methods for their populace [...]

Fuente: PubMed "Cannabis"

Letter to the Editor: On the Reluctant Decarboxylation of THCA-B

Cannabis Cannabinoid Res. 2021 Mar 24. doi: 10.1089/can.2021.0003. Online ahead of print.NO ABSTRACTPMID:33998891 | DOI:10.1089/can.2021.0003

Fuente: PubMed "Cannabis"

Symptoms and Extraintestinal Manifestations in Active Cannabis Users with Inflammatory Bowel Disease

Cannabis Cannabinoid Res. 2021 Mar 24. doi: 10.1089/can.2020.0155. Online ahead of print.ABSTRACTIntroduction: Cannabis use is common in the setting of inflammatory bowel disease (IBD). [...]

Fuente: PubMed "Cannabis"

The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review of In Vivo Studies

Cannabis Cannabinoid Res. 2021 Apr 28. doi: 10.1089/can.2020.0105. Online ahead of print.ABSTRACTIntroduction: Some cannabinoids have been identified as anti-inflammatory agents; however, [...]

Fuente: PubMed "Cannabis"

The Impact of Cannabidiol on the Induction of Isoflurane Anesthesia and Recovery in Wistar Rats

Cannabis Cannabinoid Res. 2021 May 11. doi: 10.1089/can.2021.0014. Online ahead of print.ABSTRACTBackground: Beside others, neuroinhibitory and sedative effects of CBD were documented. [...]

Fuente: PubMed "Cannabis"

A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: International Cannabinoid Research Society ICRS

A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: ICRS

Presenting the outputs of the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: International Cannabinoid Research Society ICRS

Presenting the outputs of the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: ICRS

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

Haroutounian S, Arendt-Nielsen L, Belton J, Blyth FM, Degenhardt L, Di Forti M, Eccleston C, Finn DP, Finnerup NB, Fisher E, Fogarty AE, Gilron I, Hohmann AG, Kalso E, Krane E, Mohiuddin [...]

Fuente: International Cannabinoid Research Society ICRS

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

Haroutounian S, Arendt-Nielsen L, Belton J, Blyth FM, Degenhardt L, Di Forti M, Eccleston C, Finn DP, Finnerup NB, Fisher E, Fogarty AE, Gilron I, Hohmann AG, Kalso E, Krane E, Mohiuddin [...]

Fuente: ICRS

International Association for the Study of Pain presidential task force on cannabis and cannabinoid analgesia position statement

Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N and Rice AS Pain (2021) Link to abstract

Fuente: International Cannabinoid Research Society ICRS

International Association for the Study of Pain presidential task force on cannabis and cannabinoid analgesia position statement

Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N and Rice AS Pain (2021) Link to abstract

Fuente: ICRS

IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Haroutounian, Simon, Arendt-Nielsen, Lars, Belton, Joletta, Blyth, Fiona M., Degenhardt, Louisa, Di Forti, Marta, Eccleston, Christopher, Finn, David P., Finnerup, Nanna B, Fisher, Emma, [...]

Fuente: International Cannabinoid Research Society ICRS

IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Haroutounian, Simon, Arendt-Nielsen, Lars, Belton, Joletta, Blyth, Fiona M., Degenhardt, Louisa, Di Forti, Marta, Eccleston, Christopher, Finn, David P., Finnerup, Nanna B, Fisher, Emma, [...]

Fuente: ICRS

Preliminary experiments on the chemistry and pharmacology of cannabis

Gill EW, Paton WD and Pertwee RG Nature (1970) 228: 134-6 There are at least six pharmacologically effective components of cannabis. Their effects on mice include a lowering of [...]

Fuente: International Cannabinoid Research Society ICRS

Preliminary experiments on the chemistry and pharmacology of cannabis

Gill EW, Paton WD and Pertwee RG Nature (1970) 228: 134-6 There are at least six pharmacologically effective components of cannabis. Their effects on mice include a lowering of [...]

Fuente: ICRS

Relative pharmacological potency in mice of optical isomers of delta 1-tetrahydrocannabinol

Jones G, Pertwee RG, Gill EW, Paton WD, Nilsson IM, Widman M and Agurell S Biochem Pharmacol (1974) 23: 439-46 The tritium-labelled unnatural enantiomorph of Δ1-tetrahydrocannabinol(Δ1-THC) [...]

Fuente: International Cannabinoid Research Society ICRS

Relative pharmacological potency in mice of optical isomers of delta 1-tetrahydrocannabinol

Jones G, Pertwee RG, Gill EW, Paton WD, Nilsson IM, Widman M and Agurell S Biochem Pharmacol (1974) 23: 439-46 The tritium-labelled unnatural enantiomorph of Δ1-tetrahydrocannabinol(Δ1-THC) [...]

Fuente: ICRS

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Paton WD and Pertwee RG Br J Pharmacol (1972) 44: 250-61 Link to abstract 1. Cannabis extract prolonged sleeping time in mice in a thermally neutral environment (30-32 degrees [...]

Fuente: International Cannabinoid Research Society ICRS

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Paton WD and Pertwee RG Br J Pharmacol (1972) 44: 250-61 Link to abstract 1. Cannabis extract prolonged sleeping time in mice in a thermally neutral environment (30-32 degrees [...]

Fuente: ICRS

Serum cannabidiol, THC, and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles

Hannon MB, Deabold KA, Talsma BN, Lyubimov A, Iqbal A, Zakharov A, Gamble LJ and Wakshlag JJ J Vet Pharmacol Ther (2020) Link to abstract Cannabinoids hold promise for treating [...]

Fuente: International Cannabinoid Research Society ICRS

Serum cannabidiol, THC, and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles

Hannon MB, Deabold KA, Talsma BN, Lyubimov A, Iqbal A, Zakharov A, Gamble LJ and Wakshlag JJ J Vet Pharmacol Ther (2020) Link to abstract Cannabinoids hold promise for treating [...]

Fuente: ICRS

Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy

Colangeli R, Morena M, Pittman QJ, Hill MN and Teskey GC J Neurosci (2020) 40: 6068-6081 Link to abstract Epilepsy is often associated with emotional disturbances and the endocannabinoid [...]

Fuente: International Cannabinoid Research Society ICRS

Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core

Manz KM, Ghose D, Turner BD, Taylor A, Becker J, Grueter CA and Grueter BA Cell Rep (2020) 32: 107971 Link to abstract Synaptic plasticity is a key mechanism of learning and [...]

Fuente: International Cannabinoid Research Society ICRS

Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core

Manz KM, Ghose D, Turner BD, Taylor A, Becker J, Grueter CA and Grueter BA Cell Rep (2020) 32: 107971 Link to abstract Synaptic plasticity is a key mechanism of learning and [...]

Fuente: ICRS

Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

Cabanero D, Ramirez-Lopez A, Drews E, Schmole A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A and Maldonado R Elife 2020 Jul [...]

Fuente: International Cannabinoid Research Society ICRS

Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

Cabanero D, Ramirez-Lopez A, Drews E, Schmole A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A and Maldonado R Elife 2020 Jul [...]

Fuente: ICRS

A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam

VanLandingham KE, Crockett J, Taylor L and Morrison G J Clin Pharmacol (2020) Link to abstract We investigated the effects of cannabidiol (CBD; 21-day maintenance dose) on the [...]

Fuente: International Cannabinoid Research Society ICRS

A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam

VanLandingham KE, Crockett J, Taylor L and Morrison G J Clin Pharmacol (2020) Link to abstract We investigated the effects of cannabidiol (CBD; 21-day maintenance dose) on the [...]

Fuente: ICRS

Glucose metabolism links astroglial mitochondria to cannabinoid effects

Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gomez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, [...]

Fuente: International Cannabinoid Research Society ICRS

Glucose metabolism links astroglial mitochondria to cannabinoid effects

Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gomez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, [...]

Fuente: ICRS

The association of dietary patterns with endocannabinoids levels in overweight and obese women

Yagin NL, Hajjarzadeh S, Aliasgharzadeh S, Aliasgari F and Mahdavi R Lipids Health Dis (2020) 19: 161 Link to abstract Background Higher levels of anandamide (AEA) and 2-arachidonoylglycer [...]

Fuente: International Cannabinoid Research Society ICRS

In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous THC fail to produce antinociceptive effects in healthy human volunteers

Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, Jr. and D’Souza DC Psychopharmacology (Berl) (2020) Link to abstract Cannabinoids [...]

Fuente: International Cannabinoid Research Society ICRS

In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous THC fail to produce antinociceptive effects in healthy human volunteers

Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, Jr. and D’Souza DC Psychopharmacology (Berl) (2020) Link to abstract Cannabinoids [...]

Fuente: ICRS

The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders

Lujan MA and Valverde O Front Behav Neurosci (2020) 14: 109 Link to abstract During the last decades, researchers have investigated the functional relevance of adult hippocampal [...]

Fuente: International Cannabinoid Research Society ICRS

The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders

Lujan MA and Valverde O Front Behav Neurosci (2020) 14: 109 Link to abstract During the last decades, researchers have investigated the functional relevance of adult hippocampal [...]

Fuente: ICRS

Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D

Fuente: International Cannabinoid Research Society ICRS

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

Fuente: International Cannabinoid Research Society ICRS

Two-weeks treatment with cannabidiol improves biophysical and behavioral deficits associated with experimental type-1 diabetes

Fuente: International Cannabinoid Research Society ICRS

Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids Abused by Humans

Fuente: International Cannabinoid Research Society ICRS

The L-alpha-lysophosphatidylinositol/GPR55 system induces the development of non-alcoholic steatosis and steatohepatitis

Fuente: International Cannabinoid Research Society ICRS

Cannabinoids and psychotic symptoms: A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Fuente: International Cannabinoid Research Society ICRS

Deconstructing the neurobiology of cannabis use disorder

Fuente: International Cannabinoid Research Society ICRS

Deconstructing the neurobiology of cannabis use disorder

Fuente: ICRS

Cannabis Exposure Enhances Subcortical Control of Nucleus Accumbens Activity

Fuente: International Cannabinoid Research Society ICRS

Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

Fuente: International Cannabinoid Research Society ICRS

Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

Fuente: ICRS

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions

Fuente: International Cannabinoid Research Society ICRS