Cannabis use and electronic cigarette use: The role of dual use on use frequency and related problems

Psychiatry Res. 2021 Jul 19;304:114126. doi: 10.1016/j.psychres.2021.114126. Online ahead of print.ABSTRACTDespite high rates of use of both cannabis and electronic nicotine delivery [...]

Fuente: PubMed "Cannabis"

Cannabis use and obesity-traits: A Mendelian randomization study

Drug Alcohol Depend. 2021 Jun 25;226:108863. doi: 10.1016/j.drugalcdep.2021.108863. Online ahead of print.ABSTRACTBACKGROUND: Observational studies suggested that cannabis use is associated [...]

Fuente: PubMed "Cannabis"

Pediatric surgery and future risk of cocaine, opioid, cannabis, and other substance use in women: longitudinal cohort study

Drug Alcohol Depend. 2021 Jul 21;226:108902. doi: 10.1016/j.drugalcdep.2021.108902. Online ahead of print.ABSTRACTBACKGROUND: Substance use is problematic in young women, particularly [...]

Fuente: PubMed "Cannabis"

Young adult cannabis use disorder treatment admissions declined as past month cannabis use increased in the U.S.: An analysis of states by year, 2008-2017

Addict Behav. 2021 Jul 15;123:107049. doi: 10.1016/j.addbeh.2021.107049. Online ahead of print.ABSTRACTOBJECTIVE: This short communication reports on the association of annual measures [...]

Fuente: PubMed "Cannabis"

Cannabidiol Confers Neuroprotection in Rats in a Model of Transient Global Cerebral Ischemia: Impact of Hippocampal Synaptic Neuroplasticity

Mol Neurobiol. 2021 Jul 24. doi: 10.1007/s12035-021-02479-7. Online ahead of print.ABSTRACTEvidence for the clinical use of neuroprotective drugs for the treatment of cerebral ischemia [...]

Fuente: PubMed "Cannabis"

Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts

Arch Toxicol. 2021 Jul 24. doi: 10.1007/s00204-021-03122-z. Online ahead of print.ABSTRACTCannabidiol (CBD) is a constituent of Cannabis sativa without psychotropic activity, whose medical [...]

Fuente: PubMed "Cannabis"

Classical and Neural Network Machine Learning to Determine the Risk of Marijuana Use

Int J Environ Res Public Health. 2021 Jul 13;18(14):7466. doi: 10.3390/ijerph18147466.ABSTRACTMarijuana is the most commonly abused drug for military personnel tested at the Air Force [...]

Fuente: PubMed "Cannabis"

Conversion Characteristics of Some Major Cannabinoids from Hemp (Cannabis sativa L.) Raw Materials by New Rapid Simultaneous Analysis Method

Molecules. 2021 Jul 6;26(14):4113. doi: 10.3390/molecules26144113.ABSTRACTThis study was carried out to develop a high-performance liquid chromatography method for short-time analysis [...]

Fuente: PubMed "Cannabis"

Early Consumption of Cannabinoids: From Adult Neurogenesis to Behavior

Int J Mol Sci. 2021 Jul 12;22(14):7450. doi: 10.3390/ijms22147450.ABSTRACTThe endocannabinoid system (ECS) is a crucial modulatory system in which interest has been increasing, particularly [...]

Fuente: PubMed "Cannabis"

Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases

Int J Mol Sci. 2021 Jul 7;22(14):7302. doi: 10.3390/ijms22147302.ABSTRACTChronic inflammation is considered to be a silent killer because it is the underlying cause of a wide range of [...]

Fuente: PubMed "Cannabis"

In Utero Exposure to Δ9-Tetrahydrocannabinol Leads to Postnatal Catch-Up Growth and Dysmetabolism in the Adult Rat Liver

Int J Mol Sci. 2021 Jul 13;22(14):7502. doi: 10.3390/ijms22147502.ABSTRACTThe rates of gestational cannabis use have increased despite limited evidence for its safety in fetal life. [...]

Fuente: PubMed "Cannabis"

Influence of Cannabinoid Receptor 1 Genetic Variants on the Subjective Effects of Smoked Cannabis

Int J Mol Sci. 2021 Jul 9;22(14):7388. doi: 10.3390/ijms22147388.ABSTRACTAs many jurisdictions consider relaxing cannabis legislation and usage is increasing in North America and other [...]

Fuente: PubMed "Cannabis"

Polysubstance Use, Mood Disorders, and Chronic Conditions With Anxiety in Opioid Patients

West J Nurs Res. 2021 Jul 23:1939459211031988. doi: 10.1177/01939459211031988. Online ahead of print.ABSTRACTThis study examined the associations of polysubstance use, mood disorders, [...]

Fuente: PubMed "Cannabis"

The Periaqueductal Gray and Its Extended Participation in Drug Addiction Phenomena

Neurosci Bull. 2021 Jul 24. doi: 10.1007/s12264-021-00756-y. Online ahead of print.ABSTRACTThe periaqueductal gray (PAG) is a complex mesencephalic structure involved in the integration [...]

Fuente: PubMed "Cannabis"

Treating pain related to Ehlers-Danlos syndrome with medical cannabis

BMJ Case Rep. 2021 Jul 22;14(7):e242568. doi: 10.1136/bcr-2021-242568.ABSTRACTWe present the case of an 18-year-old woman who suffered from complications of Ehlers-Danlos syndrome (EDS). [...]

Fuente: PubMed "Cannabis"

How to Write a Cannabis Testing Textbook: A Q&A With Shaun Opie

With his book now published, Analytical Cannabis caught up with Opie to find out how he pivoted into cannabis and what tips a would-be cannabis tester should know before opening their [...]

Fuente: Analytical Cannabis Articles

Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation

Ethan B. Russo, Chris Spooner, Len May, Ryan Leslie and Venetia L. Whiteley Cannabis and Cannabinoid Research, Mary Ann Liebert, Inc. (2021) Online ahead of print. Link to abstract Backgro [...]

Fuente: International Cannabinoid Research Society ICRS

Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation

Ethan B. Russo, Chris Spooner, Len May, Ryan Leslie and Venetia L. Whiteley Cannabis and Cannabinoid Research, Mary Ann Liebert, Inc. (2021) Online ahead of print. Link to abstract Backgro [...]

Fuente: ICRS

A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: International Cannabinoid Research Society ICRS

A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: ICRS

Presenting the outputs of the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: International Cannabinoid Research Society ICRS

Presenting the outputs of the IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Soliman N, Haroutounian S, Hohmann AG, Krane E, Liao J, Macleod M, Segelcke D, Sena C, Thomas J, Vollert J, Wever K, Alaverdyan H, Barakat A, Barthlow T, Harris Bozer AL, Davidson A, [...]

Fuente: ICRS

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

Haroutounian S, Arendt-Nielsen L, Belton J, Blyth FM, Degenhardt L, Di Forti M, Eccleston C, Finn DP, Finnerup NB, Fisher E, Fogarty AE, Gilron I, Hohmann AG, Kalso E, Krane E, Mohiuddin [...]

Fuente: International Cannabinoid Research Society ICRS

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

Haroutounian S, Arendt-Nielsen L, Belton J, Blyth FM, Degenhardt L, Di Forti M, Eccleston C, Finn DP, Finnerup NB, Fisher E, Fogarty AE, Gilron I, Hohmann AG, Kalso E, Krane E, Mohiuddin [...]

Fuente: ICRS

International Association for the Study of Pain presidential task force on cannabis and cannabinoid analgesia position statement

Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N and Rice AS Pain (2021) Link to abstract

Fuente: International Cannabinoid Research Society ICRS

International Association for the Study of Pain presidential task force on cannabis and cannabinoid analgesia position statement

Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N and Rice AS Pain (2021) Link to abstract

Fuente: ICRS

IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Haroutounian, Simon, Arendt-Nielsen, Lars, Belton, Joletta, Blyth, Fiona M., Degenhardt, Louisa, Di Forti, Marta, Eccleston, Christopher, Finn, David P., Finnerup, Nanna B, Fisher, Emma, [...]

Fuente: International Cannabinoid Research Society ICRS

IASP Presidential Task Force on Cannabis and Cannabinoid Analgesia

Haroutounian, Simon, Arendt-Nielsen, Lars, Belton, Joletta, Blyth, Fiona M., Degenhardt, Louisa, Di Forti, Marta, Eccleston, Christopher, Finn, David P., Finnerup, Nanna B, Fisher, Emma, [...]

Fuente: ICRS

Preliminary experiments on the chemistry and pharmacology of cannabis

Gill EW, Paton WD and Pertwee RG Nature (1970) 228: 134-6 There are at least six pharmacologically effective components of cannabis. Their effects on mice include a lowering of [...]

Fuente: International Cannabinoid Research Society ICRS

Preliminary experiments on the chemistry and pharmacology of cannabis

Gill EW, Paton WD and Pertwee RG Nature (1970) 228: 134-6 There are at least six pharmacologically effective components of cannabis. Their effects on mice include a lowering of [...]

Fuente: ICRS

Relative pharmacological potency in mice of optical isomers of delta 1-tetrahydrocannabinol

Jones G, Pertwee RG, Gill EW, Paton WD, Nilsson IM, Widman M and Agurell S Biochem Pharmacol (1974) 23: 439-46 The tritium-labelled unnatural enantiomorph of Δ1-tetrahydrocannabinol(Δ1-THC) [...]

Fuente: International Cannabinoid Research Society ICRS

Relative pharmacological potency in mice of optical isomers of delta 1-tetrahydrocannabinol

Jones G, Pertwee RG, Gill EW, Paton WD, Nilsson IM, Widman M and Agurell S Biochem Pharmacol (1974) 23: 439-46 The tritium-labelled unnatural enantiomorph of Δ1-tetrahydrocannabinol(Δ1-THC) [...]

Fuente: ICRS

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Paton WD and Pertwee RG Br J Pharmacol (1972) 44: 250-61 Link to abstract 1. Cannabis extract prolonged sleeping time in mice in a thermally neutral environment (30-32 degrees [...]

Fuente: International Cannabinoid Research Society ICRS

Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

Paton WD and Pertwee RG Br J Pharmacol (1972) 44: 250-61 Link to abstract 1. Cannabis extract prolonged sleeping time in mice in a thermally neutral environment (30-32 degrees [...]

Fuente: ICRS

Serum cannabidiol, THC, and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles

Hannon MB, Deabold KA, Talsma BN, Lyubimov A, Iqbal A, Zakharov A, Gamble LJ and Wakshlag JJ J Vet Pharmacol Ther (2020) Link to abstract Cannabinoids hold promise for treating [...]

Fuente: International Cannabinoid Research Society ICRS

Serum cannabidiol, THC, and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles

Hannon MB, Deabold KA, Talsma BN, Lyubimov A, Iqbal A, Zakharov A, Gamble LJ and Wakshlag JJ J Vet Pharmacol Ther (2020) Link to abstract Cannabinoids hold promise for treating [...]

Fuente: ICRS

Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy

Colangeli R, Morena M, Pittman QJ, Hill MN and Teskey GC J Neurosci (2020) 40: 6068-6081 Link to abstract Epilepsy is often associated with emotional disturbances and the endocannabinoid [...]

Fuente: International Cannabinoid Research Society ICRS

Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core

Manz KM, Ghose D, Turner BD, Taylor A, Becker J, Grueter CA and Grueter BA Cell Rep (2020) 32: 107971 Link to abstract Synaptic plasticity is a key mechanism of learning and [...]

Fuente: International Cannabinoid Research Society ICRS

Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core

Manz KM, Ghose D, Turner BD, Taylor A, Becker J, Grueter CA and Grueter BA Cell Rep (2020) 32: 107971 Link to abstract Synaptic plasticity is a key mechanism of learning and [...]

Fuente: ICRS

Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

Cabanero D, Ramirez-Lopez A, Drews E, Schmole A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A and Maldonado R Elife 2020 Jul [...]

Fuente: International Cannabinoid Research Society ICRS

Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain

Cabanero D, Ramirez-Lopez A, Drews E, Schmole A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A and Maldonado R Elife 2020 Jul [...]

Fuente: ICRS

A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam

VanLandingham KE, Crockett J, Taylor L and Morrison G J Clin Pharmacol (2020) Link to abstract We investigated the effects of cannabidiol (CBD; 21-day maintenance dose) on the [...]

Fuente: International Cannabinoid Research Society ICRS

A Phase 2, Double-Blind, Placebo-Controlled Trial to Investigate Potential Drug-Drug Interactions Between Cannabidiol and Clobazam

VanLandingham KE, Crockett J, Taylor L and Morrison G J Clin Pharmacol (2020) Link to abstract We investigated the effects of cannabidiol (CBD; 21-day maintenance dose) on the [...]

Fuente: ICRS

Glucose metabolism links astroglial mitochondria to cannabinoid effects

Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gomez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, [...]

Fuente: International Cannabinoid Research Society ICRS

Glucose metabolism links astroglial mitochondria to cannabinoid effects

Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gomez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, [...]

Fuente: ICRS

The association of dietary patterns with endocannabinoids levels in overweight and obese women

Yagin NL, Hajjarzadeh S, Aliasgharzadeh S, Aliasgari F and Mahdavi R Lipids Health Dis (2020) 19: 161 Link to abstract Background Higher levels of anandamide (AEA) and 2-arachidonoylglycer [...]

Fuente: International Cannabinoid Research Society ICRS

In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous THC fail to produce antinociceptive effects in healthy human volunteers

Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, Jr. and D’Souza DC Psychopharmacology (Berl) (2020) Link to abstract Cannabinoids [...]

Fuente: International Cannabinoid Research Society ICRS

In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous THC fail to produce antinociceptive effects in healthy human volunteers

Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, Jr. and D’Souza DC Psychopharmacology (Berl) (2020) Link to abstract Cannabinoids [...]

Fuente: ICRS

The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders

Lujan MA and Valverde O Front Behav Neurosci (2020) 14: 109 Link to abstract During the last decades, researchers have investigated the functional relevance of adult hippocampal [...]

Fuente: International Cannabinoid Research Society ICRS

The Pro-neurogenic Effects of Cannabidiol and Its Potential Therapeutic Implications in Psychiatric Disorders

Lujan MA and Valverde O Front Behav Neurosci (2020) 14: 109 Link to abstract During the last decades, researchers have investigated the functional relevance of adult hippocampal [...]

Fuente: ICRS

Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D

Fuente: International Cannabinoid Research Society ICRS

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

Fuente: International Cannabinoid Research Society ICRS

Two-weeks treatment with cannabidiol improves biophysical and behavioral deficits associated with experimental type-1 diabetes

Fuente: International Cannabinoid Research Society ICRS

Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids Abused by Humans

Fuente: International Cannabinoid Research Society ICRS

The L-alpha-lysophosphatidylinositol/GPR55 system induces the development of non-alcoholic steatosis and steatohepatitis

Fuente: International Cannabinoid Research Society ICRS

Cannabinoids and psychotic symptoms: A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Fuente: International Cannabinoid Research Society ICRS

Deconstructing the neurobiology of cannabis use disorder

Fuente: International Cannabinoid Research Society ICRS

Deconstructing the neurobiology of cannabis use disorder

Fuente: ICRS

Cannabis Exposure Enhances Subcortical Control of Nucleus Accumbens Activity

Fuente: International Cannabinoid Research Society ICRS

Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

Fuente: International Cannabinoid Research Society ICRS

Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

Fuente: ICRS

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions

Fuente: International Cannabinoid Research Society ICRS