Fecha de publicación:
29/07/2021
Fuente: International Cannabinoid Research Society ICRS
Krista M Lisdahl, Susan Tapert, Kenneth J Sher, Raul Gonzalez, Sara Jo Nixon, Sarah W Feldstein Ewing, Kevin P Conway, Alex Wallace, Ryan Sullivan, Kelah Hatcher, Christine Kaiver, Wes Thompson, Chase Reuter, Hauke Bartsch, Natasha E Wade, Joanna Jacobus, M D Albaugh, N Allgaier, A P Anokhin, K Bagot, F C Baker, M T Banich, D M Barch, A Baskin-Sommers, F J Breslin, S A Brown, V Calhoun, B J Casey, B Chaarani, L Chang, D B Clark, C Cloak, R T Constable, L B Cottler, R K Dagher, M Dapretto, A Dick, E K Do, N U F Dosenbach, G J Dowling, D A Fair, P Florsheim, J J Foxe, E G Freedman, N P Friedman, H P Garavan, D G Gee, M D Glantz, P Glaser, M R Gonzalez, K M Gray, S Grant, F Haist, S Hawes, S G Heeringa, R Hermosillo, M M Herting, J M Hettema, J K Hewitt, C Heyser, E A Hoffman, K D Howlett, R S Huber, M A Huestis, L W Hyde, W G Iacono, A Isaiah, M Y Ivanova, R S James, T L Jernigan, N R Karcher, J M Kuperman, A R Laird, C L Larson, K H LeBlanc, M F Lopez, M Luciana, B Luna, H H Maes, A T Marshall, M J Mason, E McGlade, A S Morris, C Mulford, B J Nagel, G Neigh, C E Palmer, M P Paulus, D Pecheva, D Prouty, A Potter, L I Puttler, N Rajapakse, J M Ross, M Sanchez, C Schirda, J Schulenberg, C Sheth, P D Shilling, E R Sowell, N Speer, L Squeglia, C Sripada, J Steinberg, M T Sutherland, R Tomko, K Uban, S Vrieze, S R B Weiss, D Wing, D A Yurgelun-Todd, R A Zucker, Mary M Heitzeg and ABCD Consortium
Drug Alcohol Depend (2021) Jul 29;227:108946. Online ahead of print.
Link to abstract
Background: The Adolescent Brain Cognitive Development Study (ABCD Study®) is an open-science, multi-site, prospective, longitudinal study following over 11,800 9- and 10-year-old youth into early adulthood. The ABCD Study aims to prospectively examine the impact of substance use (SU) on neurocognitive and health outcomes. Although SU initiation typically occurs during teen years, relatively little is known about patterns of SU in children younger than 12.
Methods: This study aims to report the detailed ABCD Study® SU patterns at baseline (n = 11,875) in order to inform the greater scientific community about cohort’s early SU. Along with a detailed description of SU, we ran mixed effects regression models to examine the association between early caffeine and alcohol sipping with demographic factors, externalizing symptoms and parental history of alcohol and substance use disorders (AUD/SUD).
Primary results: At baseline, the majority of youth had used caffeine (67.6 %) and 22.5 % reported sipping alcohol (22.5 %). There was little to no reported use of other drug categories (0.2 % full alcohol drink, 0.7 % used nicotine, <0.1 % used any other drug of abuse). Analyses revealed that total caffeine use and early alcohol sipping were associated with demographic variables (p’s<.05), externalizing symptoms (caffeine p = 0002; sipping p = .0003), and parental history of AUD (sipping p = .03).
Conclusions: ABCD Study participants aged 9-10 years old reported caffeine use and alcohol sipping experimentation, but very rare other SU. Variables linked with early childhood alcohol sipping and caffeine use should be examined as contributing factors in future longitudinal analyses examining escalating trajectories of SU in the ABCD Study cohort.
