PLATFORM FOR GENE EDITING IN PLANTS

Fuente: WIPO "tomato"
The present invention relates to a composition comprising a cationic polymer; a Cas protein or a nucleic acid sequence encoding a Cas protein; and a guide RNA or a nucleic acid sequence encoding a guide RNA. The cationic polymer is adapted to assemble into a nanoparticle with the Cas protein, or nucleic acid encoding the same, and the guide RNA. The cationic polymer is also adapted to deliver the Cas protein and the guide RNA, or nucleic acids encoding the same, into a plant cell. The present invention also relates to methods of generating a plant with an edited genome using the compositions.