Fuente: WIPO "tomato" Described are nucleic acids that can be used for guide nucleic acid expression such as nucleic acids that comprise a polII promoter; an expression gene that is operably associated with the polII promoter; and a guide nucleic acid that is in the 3' untranslated region (UTR) of the expression gene. The expression gene may have a length of about 200, 225, 250, 275, 300, 325, or 350 nucleotides to about 375, 400, 425, 450, 475, 500, 525, 550, 575, or 600 nucleotides.