Fuente: WIPO "tomato" The disclosure relates to methods for enhancing production of a heterologous protein in a plant or plant cell by inhibiting aspartic protease AED3-1. Also provided are plants and plant cells with enhanced production of a heterologous protein, wherein the plant or plant cell has reduced or loss of function of AED3-1. Further provided are shRNAs and vectors for use in enhancing production of a heterologous protein in a plant or plant cell.