Fuente: WIPO "tomato" The present invention provides a combination of at least one carotenoid and inulin for use in affecting the gut microbiota in a subject suffering from IBS. Also provided is a combination of at least one carotenoid and inulin for use in affecting the gut microbiota in a subject suffering from overweight or obesity. The combination can be used as a medicament, a dietary supplement, or a food supplement. Preferably, the combination is for use in affecting the gut microbiota in a human IBS subject or overweight subject in comparison to the administration/consumption of inulin alone and the carotenoid alone.