Fecha de publicación: 27/10/2024 Fuente: Foods - Revista científica (MDPI) Foods, Vol. 13, Pages 3422: Bergamot (Citrus bergamia), a (Poly)Phenol-Rich Source for Improving Osteosarcopenic Obesity: A Systematic Review
Foods doi: 10.3390/foods13213422
Authors:
Giuseppe Mazzola
Mariangela Rondanelli
Giovanna Baron
Roberta Zupo
Fabio Castellana
Maria Lisa Clodoveo
Clara Gasparri
Gaetan Claude Barrile
Michela Seniga
Luca Matteo Schiavi
Alessia Moroni
Sukru Gulec
Patrizia Riso
Simone Perna

This systematic review investigates the potential of bergamot, a polyphenol-rich citrus fruit, in improving osteosarcopenic obesity, a condition characterized by the simultaneous presence of osteoporosis, obesity, and sarcopenia. Bergamot extracts have been suggested to possess several pharmacological properties, including anti-inflammatory and antioxidant effects, which could be useful in the management of age-related diseases and neuromuscular health. The review highlights the promising effects of bergamot extracts on skeletal muscle mass and function, particularly in the context of obesity, metabolic syndrome, osteosarcopenic obesity, and osteoporosis. Furthermore, some studies have shown that bergamot extracts can improve the metabolic balance, endothelial function, and maximal oxygen uptake in athletes, highlighting their potential benefits for skeletal muscle health. Taken together, these results suggest that bergamot extracts, especially those rich in polyphenols, may be a valuable adjunct in the management of osteosarcopenic obesity and other associated clinical conditions involving pro-inflammatory effects on organs and tissues.