Fuente: PubMed "Cannabis" J Drug Educ. 2026 Jul 10:472379261464401. doi: 10.1177/00472379261464401. Online ahead of print.ABSTRACTComorbid cannabis use is common among individuals seeking treatment for alcohol and substance use disorders, yet research on cannabis craving within polysubstance using samples remains limited and has largely relied on traditional, unidimensional models of craving. The current study sought to provide support for a relatively novel conceptualization of cannabis craving (i.e., Ambivalence Model of Craving) among those receiving treatment for substance use disorders and reporting polysubstance use. Specifically, adults receiving inpatient treatment (N = 140) for substance use disorders completed a cue-reactivity task rating approach and avoidance inclinations after viewing alcohol and drug-related images, including cannabis. Latent profile analysis identified five groups: approach, avoidance, indifference, high ambivalence, and moderate ambivalence. Approach and high ambivalence groups reported greater cannabis use and more substance use related problems, whereas indifference and avoidance groups reported lower use. The approach and high ambivalence groups also endorsed stronger social (i.e., to facilitate social interactions), enhancement (i.e., to increase positive affect), expansion (i.e., to alter perceptual and cognitive experiences), and coping (i.e., to manage negative affect) motives for cannabis relative to the other groups. Overall, findings support the AMC as a multidimensional model of cannabis craving and highlight clinically meaningful subgroups in a polysubstance inpatient sample, though findings should be considered preliminary and replicated in future research.PMID:42429303 | DOI:10.1177/00472379261464401