The invention discloses CBD tobacco juice with a hemp taste and a preparation method of the CBD tobacco juice. The CBD tobacco juice with the hemp taste comprises the following components in percentage by mass: 30%-60% of propylene glycol, 30%-60% of glycerol, 1%-5% of a hemp floral leaf extract, 1%-5% of nicotine salt and 0.1%-2% of cannabidiol. The technical problem that the cigarette liquid is poor in effect of replacing cigarettes in smoking feeling is solved.