Fuente: WIPO "industrial hemp" The invention discloses an industrial hemp extract composition liposome, and a preparation method and application thereof, and belongs to the technical field of cosmetics. The industrial hemp extract composition liposome comprises the following raw materials in percentage by mass: 0.1-5% of a herba centellae extract, 0.1-5% of a herba portulacae extract, 0.1-5% of a Chinese herbaceous peony extract, 0.1-5% of an industrial hemp extract, 1-10% of hydrogenated lecithin, 1-10% of hydrogenated castor oil, 0.1-2% of coco-sulphobetaine, 1-5% of 0.5 percent HA hyaluronic acid, 1-10% of glycerol, 0.5-5% of soybean lecithin, 0.5-10% of trehalose, 0.5-2% of vitamin E and the balance of deionized water. The industrial hemp extract composition liposome disclosed by the invention has the characteristics of high stability, good solubility, anti-inflammation, anti-sensitivity, acne removal, moisturizing and repairing; the active components in the industrial hemp extract composition liposome can break through the skin barrier; the improvement effect is remarkable; and the industrial hemp extract composition liposome has a good application prospect.