Fuente: WIPO "hemp" The present invention provides compositions comprising polymers and biologically active compounds, especially polymeric drug delivery systems. More specifically, the present invention provides ammonium and/or phosphonium-containing polymers and/or block copolymers as a viable and improved option for gene delivery. In an embodiment, the present invention provides a method of using a composition comprising a block copolymer that comprises: a stabilization block and a complexation block, and optionally an endosomolytic block for nonviral gene delivery. Preferred compositions include such co-polymers, wherein the complexation block is chosen from polymers of styrenic-based phosphonium-containing monomers chosen from: (F) wherein X is phosphorus; R is Cl-24 alkyl; and n is a number ranging from 2 to 1,000.