The present invention relates to yeast cells capable of producing Δ(12) desaturated fatty acyl-CoAs and optionally fatty alcohols, said yeast cells expressing heterologous Δ(12) desaturases capable of introducing a double bond at position (12), i. e. a double bond between the carbon at position (12) and the carbon at position (13), in a saturated or desaturated fatty acyl-CoA having a carbon chain length of at least (13).