Fuente: PubMed "agrofood sustainability" Adv Colloid Interface Sci. 2025 Dec 19;349:103760. doi: 10.1016/j.cis.2025.103760. Online ahead of print.ABSTRACTThe nanoscale structural regulation of starch molecules involving tailored nanostarches has gained growing attention due to the high biocompatibility, processability, and tunable biodegradability upon sustainable developing prospect. However, single-component starch materials often have limitations for multifunctional applications in the human body, for both in vivo and in vitro settings. Starch-derived materials with modified nanostructure by proteins, lipids, inorganic components, etc., enable the generation of a wide range of high-performance nanocomposites, which are increasingly used as functional matrices and carriers. These broadly-defined "nanostarch"-based materials show great potential for both human internal and external applications. Usage scenarios are internally in functional foods, drug delivery, and tissue engineering, and externally in smart packaging, flexible optoelectronic sensing, and environmental remediation. Overall, we summarize and review the advances in the state-of-art fabrication of starch nanostructure-modified composites as cutting-edge functional materials, with their versatile applications contributing to human health and sustainability.PMID:41422767 | DOI:10.1016/j.cis.2025.103760