Scalable mechanochemical synthesis of amides using bead milling technology

Fuente: Green Chemistry
Green Chem., 2026, Advance ArticleDOI: 10.1039/D5GC04764A, PaperPietro Caboni, Andrea Porcheddu, Sándor B. Ötvös, C. Oliver KappeA scalable protocol for mechanochemical amide bond formation was developed using a commercially available agitator bead mill without requiring reagent excess, added base or large quantities of organic solvent, significantly reducing waste generation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry