Fuente: Wipo "Sensorization" Various examples are directed to systems and methods for generating an estimated analyte value, such as a glucose value. An analyte sensor system may access a first sensor signal from an in vivo analyte sensor and a first temperature signal from the ex vivo temperature sensor. The analyte sensor system may generate a first analyte sensor temperature based at least in part on the first temperature signal and generate a first estimated analyte value based at least in part on the first sensor signal and the first temperature-compensated sensitivity. Further examples are directed to using a non-analyte background signal.