Fuente: Wipo "digitalization" In some embodiments, a method for encrypting a file includes receiving a file comprising file data and file metadata; retrieving a genomic differentiation object and genomic regulation instructions that define a set of operations that modify the genomic differentiation object; modifying the genomic differentiation object into a modified genomic differentiation object based on the genomic regulation instructions; extracting a sequence of bits from a predetermined set of bit locations of the file metadata; generating a genomic engagement factor based on the modified genomic differentiation object and the extracted sequence; and encrypting at least one portion of the file data using the genomic engagement factor.