Fuente: Wipo "digitalization" In one embodiment, a digital pathology image processing system receives digital pathology images of histologic samples. Physical characteristics of a first histologic sample associated with a first digital pathology image are assessed. The first digital pathology image is segmented based on one or more regions of the first digital pathology image corresponding to tumor bed. The first digital pathology image is also segmented based on one or more regions corresponding to one or more predetermined histologic features. An assessment is generated regarding a specified condition in the first histologic sample based on the one or more regions corresponding to tumor bed and the one or more regions corresponding to the one or more predetermined histologic features. The condition may be associated with a level or degree of pathologic response. A user interface may display information related to the assessment.