Fuente: Wipo "BigData" The embodiment of the invention discloses an infectious disease transmission path generation and early warning method and device based on big data. A specific embodiment of the method comprises the following steps: generating a diagnosed person set and a contact person set according to urban infectious disease data; determining an activity point sequence of each diagnosed person to obtain an activity point sequence set of the diagnosed persons; clustering the activity point sequence of each diagnosed person to obtain a high-risk region set; determining the urban personnel meeting a preset high-risk crowd condition as high-risk personnel, and obtaining a high-risk personnel set; determining an association node corresponding to each high-risk region to obtain a high-risk association node set; generating an infectious disease transmission map; and generating an infectious disease transmission path set according to the infectious disease transmission map, and generating an infectious disease transmission thermodynamic diagram according to the infectious disease transmission path set. According to the embodiment, the infectious disease transmission path can be tracked, and the infectious disease diffusion risk and the social prevention and control cost are reduced.