Fuente: Materials Metasurface-based antennas have emerged as a revolutionary technology in biomedical applications owing to their capacity to manipulate electromagnetic waves with exceptional precision and efficiency. These flat structures, made up of tiny units smaller than the wavelength of light, allow for great control over how waves move, enabling tasks like directing beams, focusing them, and changing their polarization. These surfaces possess significant potential in biomedical applications, encompassing imaging, sensing, therapies, and brain interfaces. In biomedical fields, metasurface antennas are crucial for improving imaging systems, including microwave and millimeter-wave imaging for early cancer diagnosis and brain activity monitoring. Their small size, simple design, and ability to work with flexible materials make them ideal for wearable and implantable devices, addressing challenges in noninvasive testing and treatment. Additionally, metasurface designs are improved to achieve higher gain, better radiation patterns, and specific frequency selection, which are important for uses like wireless power transfer in medical implants and precise targeting in heat treatments. Recent advancements in reconfigurable metasurfaces that use adjustable materials like liquid crystals or phase-change substances improve their ability to adapt quickly for real-time biological sensing and diagnostics. Challenges including biocompatibility, downsizing, and integration with current medical technologies continue to be subjects of active investigation. This chapter examines the concepts, applications, problems, and future trajectories of metasurface-based antennas in biomedical engineering, substantiated by recent research and citations. This chapter highlights the latest developments in metasurface-based antennas for biomedical applications, highlighting their potential to revolutionize noninvasive imaging, wearable health monitoring, and wireless medical devices. Metasurface antennas, through novel designs and material breakthroughs, are poised to transform biomedical engineering, providing unparalleled solutions for patient care and diagnostics.