Diastereoselective Construction of Complex Spiroheterocycles via γ-C(sp³)–H Functionalization of 1,1-Disubstituted Cyclohexanes with Diverse Bifunctional Reagents

Fuente: Green Chemistry
Green Chem., 2026, Accepted ManuscriptDOI: 10.1039/D5GC06338H, PaperMohana Reddy Mutra, T. L. Chandana, Hsing-Yin Chen, Yun-Jou Wang, Jeh-Jeng WangSelective γ-C(sp³)–H functionalization within radical cascade sequences for constructing spiroheterocycles remains a significant challenge in organic synthesis, particularly when targeting sterically encumbered, conformationally rigid scaffolds with high stereocontrol. Herein, we...The content of this RSS Feed (c) The Royal Society of Chemistry